Chitin and Chitosan as Direct Compression Excipients in Pharmaceutical Applications
نویسندگان
چکیده
منابع مشابه
Chitin and Chitosan as Direct Compression Excipients in Pharmaceutical Applications
Despite the numerous uses of chitin and chitosan as new functional materials of high potential in various fields, they are still behind several directly compressible excipients already dominating pharmaceutical applications. There are, however, new attempts to exploit chitin and chitosan in co-processing techniques that provide a product with potential to act as a direct compression (DC) excipi...
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This study was aimed at evaluating chitosan-microcrystalline cellulose blends as direct compression excipients. Crab shell chitosan, α-lactose monohydrate, and microcrystalline cellulose powders were characterized. Blends of the microcrystalline cellulose and chitosan in ratios 9 : 1, 4 : 1, 2 : 1, and 1 : 1 as direct compression excipients were made to constitute 60% of metronidazole tablets. ...
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Chitin and chitosan are the most abundant natural amino polysaccharide that are non-toxic, biodegradable and biocompatible. They have become of great interest not only as an underutilized resource, but also as a new functional material of high potential in various fields. They are biopolymers having immense structural possibilities for chemical and mechanical modifications to generate novel pro...
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Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional de México. Av. Wilfrido Massieu s/n esq. M. Stampa, Unidad Profesional Adolfo López Mateos, Col. Industrial Vallejo, C. P. 07738, D. F., México. E-mail: [email protected]; [email protected] A rt ic le Brazilian Journal of Pharmaceutical Sciences vol. 51, n. 1, jan./mar., 2015 http://dx.doi.org/10.1590/S1984-82...
متن کاملChitin and chitosan: Chemistry, properties and applications
Chitin and chitosan are considerably versatile and promising biomaterials. The deacetylated chitin derivative, chitosan is more useful and interesting bioactive polymer. Despite its biodegradability, it has many reactive amino side groups, which offer possibilities of chemical modifications, formation of a large variety of useful derivatives that are commercially available or can be made availa...
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ژورنال
عنوان ژورنال: Marine Drugs
سال: 2015
ISSN: 1660-3397
DOI: 10.3390/md13031519